Journal of Drugs in Dermatology
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K. K. Reddy, J. A. Brauer, M. H. Idriss, et al.
incidences of hyperpigmentation and scarring. 8 In the current
study, test spots were performed, and the Nd: YAG laser device
utilized integrates sapphire- window contact cooling, which likely
promoted the improved safety observed in Fitzpatrick skin types I
to III. Melanin remains a competing chromophore with some absorption
at both 532- nm and 585- to 595- nm wavelengths, making
caution prudent when considering treatment of PWS in tanned
skin or in Fitzpatrick skin types III and above.
In summary, the studied 532- nm, frequency- doubled Nd: YAG laser
with short pulse widths, FDA approved for the treatment of cutaneous
vascular lesions ( Excel V; Cutera), demonstrated 1% to 25% to
51% to 75% improvement in PWS color after one treatment session
in individuals with a subject- reported history of mild or unsatisfactory
response to PDL. Self- limited hypopigmentation was observed
in 1 patient, and no hyperpigmentation or scarring was observed.
Further studies are encouraged to evaluate effects of this FDAapproved,
short pulse width, 532- nm, frequency- doubled Nd: YAG
laser system in improving treatment of cutaneous vascular lesions.
Study funding was provided by the device manufacturer, Cutera
Inc ( Brisbane, CA).
Drs. Reddy, Brauer, Anolik, Bernstein, Brightman, Hale, Karen,
Weiss, and Geronemus served as investigators for Cutera, Inc. The
other authors have no relevant conflicts of interest to disclose.
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Kavitha Reddy MD
E- mail:................……............................ kavithareddymd@ gmail. com
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